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Guanosine, 5-bromo-2′-deoxycytidylyl-(3′→5′)-2′-deoxycytidylyl-(3′→5′)-2′-deoxyguanylyl-(3′→5′)-2′-deoxy-

4-Amino-1-[(3S,5R,7S)-1,1-difluoro-7-hydroxy-4-oxaspiro[2.4]hept-5-yl]-2(1H)-pyrimidinone

(3S,5R,7S)-5-(6-Amino-9H-purin-9-yl)-1,1-difluoro-4-oxaspiro[2.4]heptan-7-ol

1-[(3S,5R,7S)-1,1-Difluoro-7-hydroxy-4-oxaspiro[2.4]hept-5-yl]-2,4(1H,3H)-pyrimidinedione

9-[(3S,5R,7S)-7-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1,1-difluoro-4-oxaspiro[2.4]hept-5-yl]-9H-purin-6-amine

1-[(5R,7S)-7-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1,1-difluoro-4-oxaspiro[2.4]hept-5-yl]-2,4(1H,3H)-pyrimidinedione

O-[(3S,5R,6R,7S)-5-(6-Amino-9H-purin-9-yl)-6-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,1-difluoro-4-oxaspiro[2.4]hept-7-yl] 1H-imidazole-1-carbothioate

O-[(3S,5R,6R,7S)-5-(6-Amino-9H-purin-9-yl)-7-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,1-difluoro-4-oxaspiro[2.4]hept-6-yl] 1H-imidazole-1-carbothioate

O-[(3S,5R,6R,7S)-5-(3,4-Dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-6-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,1-difluoro-4-oxaspiro[2.4]hept-7-yl] 1H-imidazole-1-carbothioate

O-[(3S,5R,7S)-5-(3,4-Dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-7-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,1-difluoro-4-oxaspiro[2.4]hept-6-yl] 1H-imidazole-1-carbothioate

(3S,5R,6R,7S)-5-(6-Amino-9H-purin-9-yl)-6-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,1-difluoro-4-oxaspiro[2.4]heptan-7-ol

1-[(3S,5R,6R,7S)-6-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1,1-difluoro-7-hydroxy-4-oxaspiro[2.4]hept-5-yl]-2,4(1H,3H)-pyrimidinedione

(3S,5R,6R,7S)-5-(6-Amino-9H-purin-9-yl)-1,1-difluoro-4-oxaspiro[2.4]heptane-6,7-diol

9-[(1S,3′aS,6′R,6′aR)-2,2-Difluorodihydro-2′,2′-dimethylspiro[cyclopropane-1,4′(3′aH)-furo[3,4-d][1,3]dioxol]-6′-yl]-6-(2,5-dimethyl-1H-pyrrol-1-yl)-9H-purine

6-(2,5-Dimethyl-1H-pyrrol-1-yl)-9-[2,3-O-(1-methylethylidene)-5-O-[(4-methylphenyl)sulfonyl]-β-D-ribofuranosyl]-9H-purine

1-[(1S,3′aS,6′R,6′aR)-2,2-Difluorodihydro-2′,2′-dimethylspiro[cyclopropane-1,4′-[4H,6H-furo[3,4-d][1,3]dioxol]-6′-yl]]-4-(1H-1,2,4-triazol-1-yl)-2(1H)-pyrimidinone

1-[(1S,3′aS,6′R,6′aR)-2,2-Difluorodihydro-2′,2′-dimethylspiro[cyclopropane-1,4′(3′aH)-furo[3,4-d][1,3]dioxol]-6′-yl]-2,4(1H,3H)-pyrimidinedione

1-[(3S,5R,6R,7S)-1,1-Difluoro-6,7-dihydroxy-4-oxaspiro[2.4]hept-5-yl]-2,4(1H,3H)-pyrimidinedione

3-Benzoyl-1-[(3S,5R,6R,7S)-1,1-difluoro-6,7-dihydroxy-4-oxaspiro[2.4]hept-5-yl]-2,4(1H,3H)-pyrimidinedione

3-Benzoyl-1-[(1S,3′aS,6′R,6′aR)-2,2-difluorodihydro-2′,2′-dimethylspiro[cyclopropane-1,4′(3′aH)-furo[3,4-d][1,3]dioxol]-6′-yl]-2,4(1H,3H)-pyrimidinedione

2388 2389 2390 2391 2392 2393 2394 2395 2396 2397

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