R1479
CAT NO.：NC00519 | CAS No.: 478182-28-4 | Purity:
97%
Quality Control:
* Storage：
Store long-term in a tightly closed container,in a cool and dry place.
* Our products are for research use only.
* All descriptions are for reference only,please take the CAS number as the standard.
Product Details
| Synonyms | 4'-azidocytidine; 4'-c-Azidocytidine;4-amino-1-((2R,3R,4S,5R)-5-azido-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one | ||
|---|---|---|---|
| CAS | 478182-28-4 | Molecular Weight | 284.23 |
| Catalog Number | NC00519 | MDL | |
| Appearance | Melting point | ||
| Purity | 97% | Boiling Point | |
| Molecular Formula | C9H12N6O5 | Flash Point | |
Description
R-1479, also known as 4'-azidocytidine, is a potent inhibitor of NS5B-dependent RNA synthesis and hepatitis C virus replication in cell culture. R-1479 is a specific inhibitor of HCV replication in the HCV subgenomic replicon system (IC(50) = 1.28 microM). The corresponding 5'-triphosphate derivative (R1479-TP) is a potent inhibitor of native HCV replicase isolated from replicon cells and of recombinant HCV polymerase (NS5B)-mediated RNA synthesis activity. R1479-TP inhibited RNA synthesis as a CTP-competitive inhibitor with a K(i) of 40 nM.
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Historical Records
| CAS No. | 478182-28-4 |
| Catalog Number | NC00519 |
| Purity | 97% |
