Synonyms | β-Pseudouridine;5-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione | ||
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CAS | 1445-07-4 | Molecular Weight | 244.20 |
Catalog Number | NC00529 | MDL | MFCD00038458 |
Appearance | Off-white to white solid | Melting point | |
Purity | 97% | Boiling Point | 598.4°C at 760 mmHg |
Molecular Formula | C9H12N2O6 | Flash Point |
GHS Pictograms |
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Signal Word | Warning | Class | |
Precautionary Statements | H302-H315-H319-H335 | UN Number | |
Hazard Statements | P261-P305+P351+P338 | Packing Group |
KO-539 is a novel, once-daily, oral investigational drug candidate targeting the menin-KMT2A/MLL protein-protein interaction for treatment of genetically defined AML patients with high unmet need; In preclinical models, KO-539 inhibits the KMT2A/MLL protein complex and has downstream effects on HOXA9/MEIS1 expression. KO-539 has received Orphan Drug Designation from the U.S. Food and Drug Administration for the treatment of AML.
CAS No. | 2140-72-9 |
Catalog Number | NC00723 |
Purity | 97% |
CAS No. | 2140-76-3 |
Catalog Number | NC00722 |
Purity | 97% |
CAS No. | 120595-72-4 |
Catalog Number | NC00721 |
Purity |
CAS No. | 2140-71-8 |
Catalog Number | NC00720 |
Purity | 97% |
CAS No. | 1445-07-4 |
Catalog Number | NC00529 |
Purity | 97% |