CAT NO.:NC00529 |  CAS No.: 1445-07-4 |  Purity: 97%        
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Product Details
Synonyms β-Pseudouridine;5-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
CAS 1445-07-4 Molecular Weight 244.20
Catalog Number NC00529 MDL MFCD00038458
Appearance Off-white to white solid Melting point
Purity 97% Boiling Point 598.4°C at 760 mmHg
Molecular Formula C9H12N2O6 Flash Point
GHS Pictograms
Signal Word Warning Class
Precautionary Statements H302-H315-H319-H335 UN Number
Hazard Statements P261-P305+P351+P338 Packing Group

KO-539 is a novel, once-daily, oral investigational drug candidate targeting the menin-KMT2A/MLL protein-protein interaction for treatment of genetically defined AML patients with high unmet need; In preclinical models, KO-539 inhibits the KMT2A/MLL protein complex and has downstream effects on HOXA9/MEIS1 expression. KO-539 has received Orphan Drug Designation from the U.S. Food and Drug Administration for the treatment of AML.

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CAS No. 1445-07-4
Catalog Number NC00529
Purity 97%